Menstrual migraines.

Menstrual Migraines

Tuesday, November 2nd, 2010
Women affected with menstrual headaches have one solid advantage – they always know beforehand when the next attack is to begin. Just therefore now, using the latest advances of the science they may meet a headache attack fully armed.
Menstrual migraines usually develop as a result of abrupt jumps of the level of sex hormones, especially of estrogens and progesterone. Migraine most likely emerges in response to level change of estrogens (increase or reduction), or to estrogen-gestogen ratio distortion.
It is interesting to notice that there is also traced direct relationship between migraine and unreasonably high level of estrogens. To begin with, in women affected with migraine, the level of estrogens is usually higher than mean values. This makes premenstrual drop of estrogens unduly abrupt. In the same way, contraceptive pills containing estrogen have an effect on the emergence of headaches.
Ten per cent of women not having affected with migraine previously have migraine pains after the beginning of administration of oral contraceptives. Migraine pains are one of the most common side effects of oral contraceptives (OC). Statistics confirms that the intake of OC and other medication containing estrogens increases significantly the frequency, duration, intensity and number of concomitant symptoms during migraine attacks.
If a woman’s head aches every month in definite days of her menstrual cycle, it is logical to suppose that the reason of the headache is in the level change of sex hormones, circulating in the blood.
Then, what is the chief matter of menstrual migraines?
Menstrual migraines are indentified as the migraines, attacks of which occur always in definite time and timed to coincide either to the moment of the beginning or the end of menstrual bleeding, or to ovulation period. Usually attacks have the character of unilateral, throbbing headaches accompanied with nausea, vomit, intolerance of bright light (dread of light) and noise. Many women before an attack have various sight distortions.
In case of classical migraine a patient always feels predecessors and pains in adverse parts of the head. More often pains are contained in the frontotemporal part. In case of non-classical migraine or ordinary migraine the pain may be localized in any part of the head or by turn – altering each other. Usually the pain is long-lasting, aching, dull and throbbing. With the course of time it may become constant and generalized.
Why not all the women have menstrual migraines? It is accounted for the fact that genetic predisposition is needed for the emergence of migraine. Some women have genetic predisposition to headaches. Also they are reported to have higher aggregation (adhesion) of thrombocytes. Due to the presence of such genetic changes these women become more vulnerable for headache factors, such as fluctuation of level of sex hormones.
For the first time ever the connection between menstrual cycle and headaches scientists detected in 1960. They found out that seventy per cent of women affected with migraine, always have attacks in the definite moment of menstrual cycle. During several years many hypotheses that would be able to explain such phenomenon were put forward. Finally it was concluded that headaches were induced by fluctuation of the level of sex hormones during a menstrual cycle. Due to this discovery the principle of treatment which helped more than eighty per cent of women to get rid of menstrual headaches was found.
Although the presence of connection between fluctuation of hormone level and occurrence of migraine is a common knowledge, the complicated chemical reactions underlying in this process have not been learnt through. Scientists turned their attention to the overactive aggregation of thrombocytes during migraine, which results in massive discharge of serotonin. This reaction appeared to be central in migraine pathogenesis, as migraine causes not only spasm of brain vessels, but influences the process of forming of painful sensation.
Thus, in women with hypersensitivity to estrogens the fluctuation of their level provokes the increase of prostaglandins. Most cells of our body synthesize prostaglandins. Their predecessors are polyunsaturated acids included into biologic membranes. They work pharmacologically on sets of physiologic functions of the body. Prostaglandins, not being true hormones, modulate action of hormones, i.e. they are mediators. Action of prostaglandins causes many processes connected with painful sensation, such as inflammation, immune and allergic reactions, likewise menstrual migraines.
Prostaglandins in body are produced by the action of three-step process. At the first stage from the vegetables and meat which a woman eats every day, there discharges fatty acid called arachidonic acid in the digestive tract. Thus, it is an easy task for women affected with menstrual migraines to get arachidonic acid.
Even if some chemical substance may be blamed for headaches, prostaglandins are the most likely ones. Moreover, scientists established the fact that an injection of prostaglandin may induce all symptoms of classical migraine including loss of eyesight.
Action mechanism of aspirin consists in blocking of synthesis of prostaglandins from arachidonic acid. Reducing production and activity of prostaglandins, aspirin and other nonsteroid anti-inflammatory medications (NAIM) are able to prevent and arrest migraine attacks.

Women affected with menstrual headaches have one solid advantage – they always know beforehand when the next attack is to begin. Just therefore now, using the latest advances of the science they may meet a headache attack fully armed.

Menstrual migraines usually develop as a result of abrupt jumps of the level of sex hormones, especially of estrogens and progesterone. Migraine most likely emerges in response to level change of estrogens (increase or reduction), or to estrogen-gestogen ratio distortion.

It is interesting to notice that there is also traced direct relationship between migraine and unreasonably high level of estrogens. To begin with, in women affected with migraine, the level of estrogens is usually higher than mean values. This makes premenstrual drop of estrogens unduly abrupt. In the same way, contraceptive pills containing estrogen have an effect on the emergence of headaches.

Ten per cent of women not having affected with migraine previously have migraine pains after the beginning of administration of oral contraceptives. Migraine pains are one of the most common side effects of oral contraceptives (OC). Statistics confirms that the intake of OC and other medication containing estrogens increases significantly the frequency, duration, intensity and number of concomitant symptoms during migraine attacks.

If a woman’s head aches every month in definite days of her menstrual cycle, it is logical to suppose that the reason of the headache is in the level change of sex hormones, circulating in the blood.

Then, what is the chief matter of menstrual migraines?

Menstrual migraines are indentified as the migraines, attacks of which occur always in definite time and timed to coincide either to the moment of the beginning or the end of menstrual bleeding, or to ovulation period. Usually attacks have the character of unilateral, throbbing headaches accompanied with nausea, vomit, intolerance of bright light (dread of light) and noise. Many women before an attack have various sight distortions.

In case of classical migraine a patient always feels predecessors and pains in adverse parts of the head. More often pains are contained in the frontotemporal part. In case of non-classical migraine or ordinary migraine the pain may be localized in any part of the head or by turn – altering each other. Usually the pain is long-lasting, aching, dull and throbbing. With the course of time it may become constant and generalized.

Why not all the women have menstrual migraines? It is accounted for the fact that genetic predisposition is needed for the emergence of migraine. Some women have genetic predisposition to headaches. Also they are reported to have higher aggregation (adhesion) of thrombocytes. Due to the presence of such genetic changes these women become more vulnerable for headache factors, such as fluctuation of level of sex hormones.

For the first time ever the connection between menstrual cycle and headaches scientists detected in 1960. They found out that seventy per cent of women affected with migraine, always have attacks in the definite moment of menstrual cycle. During several years many hypotheses that would be able to explain such phenomenon were put forward. Finally it was concluded that headaches were induced by fluctuation of the level of sex hormones during a menstrual cycle. Due to this discovery the principle of treatment which helped more than eighty per cent of women to get rid of menstrual headaches was found.

Although the presence of connection between fluctuation of hormone level and occurrence of migraine is a common knowledge, the complicated chemical reactions underlying in this process have not been learnt through. Scientists turned their attention to the overactive aggregation of thrombocytes during migraine, which results in massive discharge of serotonin. This reaction appeared to be central in migraine pathogenesis, as migraine causes not only spasm of brain vessels, but influences the process of forming of painful sensation.

Thus, in women with hypersensitivity to estrogens the fluctuation of their level provokes the increase of prostaglandins. Most cells of our body synthesize prostaglandins. Their predecessors are polyunsaturated acids included into biologic membranes. They work pharmacologically on sets of physiologic functions of the body. Prostaglandins, not being true hormones, modulate action of hormones, i.e. they are mediators. Action of prostaglandins causes many processes connected with painful sensation, such as inflammation, immune and allergic reactions, likewise menstrual migraines.

Prostaglandins in body are produced by the action of three-step process. At the first stage from the vegetables and meat which a woman eats every day, there discharges fatty acid called arachidonic acid in the digestive tract. Thus, it is an easy task for women affected with menstrual migraines to get arachidonic acid.

Even if some chemical substance may be blamed for headaches, prostaglandins are the most likely ones. Moreover, scientists established the fact that an injection of prostaglandin may induce all symptoms of classical migraine including loss of eyesight.

Action mechanism of aspirin consists in blocking of synthesis of prostaglandins from arachidonic acid. Reducing production and activity of prostaglandins, aspirin and other nonsteroid anti-inflammatory medications (NAIM) are able to prevent and arrest migraine attacks.